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Effect of subvoxel processes on non-destructive characterization of β-tricalcium phosphate bone graft substitutes

Paper ID Volume ID Publish Year Pages File Format Full-Text
1052 72 2011 12 PDF Available
Title
Effect of subvoxel processes on non-destructive characterization of β-tricalcium phosphate bone graft substitutes
Abstract

The geometric features of bone graft substitutes, such as the pore and pore interconnection sizes, are of paramount importance for their biological performance. Such features are generally characterized by micro-computed tomography (μCT). Unfortunately, the resolution of μCT is often too limited. The aim of this study was to look at the effect of μCT resolution on the geometric characterization of four different bone graft substitutes. An attempt was also made to improve the characterization of these materials by applying a subvoxelization algorithm. The results revealed that both approaches increased the accuracy of the geometric characterization. They also showed that the interconnection size in particular was affected. Comparing the results obtained from the scanned and numerical subvoxelization datasets revealed a minor difference of less than 2.5% for the porosity values. The difference for the pore sizes was up to 10%. Considerable differences of up to 35–50% were found for the interconnection sizes. The present study demonstrates how complex geometric characterization is and how important it is for biomaterial researchers to be aware of the impact of μCT resolution on the pore and pore interconnection sizes.

Keywords
Subvoxelization; Bone substitute; Characterization; Pore size; Pore interconnection size
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Effect of subvoxel processes on non-destructive characterization of β-tricalcium phosphate bone graft substitutes
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 7, Issue 11, November 2011, Pages 4045–4056
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us