fulltext.study @t Gmail

The effect of positively charged plasma polymerization on initial osteoblastic focal adhesion on titanium surfaces

Paper ID Volume ID Publish Year Pages File Format Full-Text
10754 701 2007 14 PDF Available
Title
The effect of positively charged plasma polymerization on initial osteoblastic focal adhesion on titanium surfaces
Abstract

The crucial factor of metal implant ingrowth in the bone is the rapid cellular acceptance. Therefore, the knowledge about additionally used adhesion mechanisms of osteoblasts, like their negatively charged hyaluronan coat, generates new surface functionalization strategies. Here, titanium was coated with a very thin, adherent, cross-linked, pinhole- and additive-free allylamine plasma polymer layer (PPAAm) resistant to hydrolysis and delamination and equipped with a high density of positively charged amino groups. This plasma polymer-functionalization of titanium is advantageous concerning osteoblastic focal adhesion formation as vinculin and paxillin, actin cytoskeleton development and, in consequence in differentiated cell functions, compared to a pure titanium surface—but similar such as the collagen I bonded surface via a polyethylenglycol-diacid (PEG DA)-spacer.

Keywords
Titanium; Surface modification; Plasma polymerization; Hyaluronan; Actin; Adhesion molecules
First Page Preview
The effect of positively charged plasma polymerization on initial osteoblastic focal adhesion on titanium surfaces
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 28, Issue 30, October 2007, Pages 4521–4534
Authors
, , , , , , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us