fulltext.study @t Gmail

Designing a molecularly imprinted polymer as an artificial receptor for the specific recognition of creatinine in serums

Paper ID Volume ID Publish Year Pages File Format Full-Text
10803 702 2006 7 PDF Available
Title
Designing a molecularly imprinted polymer as an artificial receptor for the specific recognition of creatinine in serums
Abstract

In this study, molecularly imprinted polymers (MIP) synthesized from two different functional monomers, β-cyclodextrin (β-CD) and 4-vinylpyridine (4-Vpy), were prepared. The crosslinkers used for these two monomers were epichlorohydrin (EPI) and divinylbenzene (DVB), respectively. It was attempted to adsorb the target molecule, creatinine, from its mixture solutions. A proper molar ratio of monomer/crosslinker for the preparation of the imprinted poly(β-CD) was 1:10. Between both polymers mentioned above, the affinity of the imprinted poly(4-Vpy−co−DVB) towards creatinine was comparably superior. The imprinted poly(4-Vpy−co−DVB) for creatinine could reach a specific binding ratio of 3.11. The imprinted poly(4-Vpy−co−DVB) was further utilized to bind creatinine from human serum samples. The binding capacity of the imprinted poly(4-Vpy−co−DVB) for creatinine from the serum samples was plotted against the creatinine concentration. From the correlation, the feasibility of the imprinted poly(4-Vpy−co−DVB) thus prepared for the target analyte, creatinine, was experimentally confirmed.

Keywords
β-cyclodextrin; 4-vinylpyridine; Creatinine; Imprinting factor; Serum
First Page Preview
Designing a molecularly imprinted polymer as an artificial receptor for the specific recognition of creatinine in serums
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 27, Issue 9, March 2006, Pages 2083–2089
Authors
, , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us