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A comparative study of calcium phosphate formation on bioceramics in vitro and in vivo

Paper ID Volume ID Publish Year Pages File Format Full-Text
10967 711 2005 10 PDF Available
Title
A comparative study of calcium phosphate formation on bioceramics in vitro and in vivo
Abstract

Formation of calcium phosphate (Ca-P) on various bioceramic surfaces in simulated body fluid (SBF) and in rabbit muscle sites was investigated. The bioceramics were sintered porous solids, including bioglass, glass-ceramics, hydroxyapatite, α-tricalcium phosphate and β-tricalcium phosphate. The ability of inducing Ca-P formation was compared among the bioceramics. The Ca-P crystal structures were identified using single-crystal diffraction patterns in transmission electron microscopy. The examination results show that ability of inducing Ca-P formation in SBF was similar among bioceramics, but considerably varied among bioceramics in vivo. Sintered β-tricalcium phosphate exhibited a poor ability of inducing Ca-P formation both in vitro and in vivo. Octacalcium phosphate (OCP) formed on the surfaces of bioglass, A-W, hydroxyapatite and α-tricalcium phosphate in vitro and in vivo. Apatite formation in physiological environments cannot be confirmed as a common feature of bioceramics.

Keywords
Calcium phosphate; Bioceramics; Simulated body fluid; Bioactivity; Transmission electron microscopy
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A comparative study of calcium phosphate formation on bioceramics in vitro and in vivo
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 26, Issue 33, November 2005, Pages 6477–6486
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
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Price was $35.95
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Full-text PDF Download
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