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Antibacterial activity of dental composites containing quaternary ammonium polyethylenimine nanoparticles against Streptococcus mutans

Paper ID Volume ID Publish Year Pages File Format Full-Text
11407 737 2006 8 PDF Available
Title
Antibacterial activity of dental composites containing quaternary ammonium polyethylenimine nanoparticles against Streptococcus mutans
Abstract

The antibacterial activity of quaternary ammonium polyethylenimine (PEI) nanoparticles embedded at 1% w/w with clinically used bonding, flowable and hybrid dental composite resins and cured by light polymerization was studied. The antibacterial activity was tested with Streptoccocus mutans by: (i) the agar diffusion test (ADT); (ii) the direct contact test; (iii) bacterial growth in the materials elute; (iv) and scanning electron microscope (SEM). Using the direct contact test, antibacterial activity (p<0.001) was found in all three types of composite resins incorporated with the synthesized nanoparticles. The effect lasted for at least 1 month. SEM demonstrated bacterial debris and no streptococcal chains at 24 h of bacterial contact. The addition of 1% w/w of nanoparticles did not affect the flexural modulus and the flexural strength of the dental composite materials.The results indicate that quaternary ammonium PEI nanoparticles immobilized in resin-based materials have a strong antibacterial activity upon contact without leach-out of the nanoparticles and without compromise in mechanical properties.

Keywords
Quaternary ammonium; Nanoparticles; Antibacterial; Dental composite; Polyethylenimine
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Antibacterial activity of dental composites containing quaternary ammonium polyethylenimine nanoparticles against Streptococcus mutans
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 27, Issue 21, July 2006, Pages 3995–4002
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us