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Effects of solvent dehydration on creep resistance of poly(vinyl alcohol) hydrogel

Paper ID Volume ID Publish Year Pages File Format Full-Text
11458 742 2007 9 PDF Available
Title
Effects of solvent dehydration on creep resistance of poly(vinyl alcohol) hydrogel
Abstract

As a synthetic replacement material for osteochondral defect repair, poly(vinyl alcohol) (PVA) hydrogels offer a great potential due to their high water content and strong mechanical integrity. To survive the high stress environment in the joint space, high creep resistance becomes one of the key requirements for hydrogel implants. We hypothesized that reducing the equilibrium water content (EWC) of hydrogels would improve their creep resistance. We investigated the effect of dehydration of PVA theta-gels in various solvent/solution media followed by rehydration in saline solution. Decreasing EWC increased the creep resistance of PVA theta-gels. The most effective medium was isopropyl alcohol for reducing the EWC and increasing the creep resistance of PVA theta-gels.

Keywords
Poly(vinyl alcohol); Poly(ethylene glycol); Hydrogel; Dehydration; Osteochondral defects
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Effects of solvent dehydration on creep resistance of poly(vinyl alcohol) hydrogel
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 28, Issue 5, February 2007, Pages 772–780
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us