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Biodegradable stents with elastic memory

Paper ID Volume ID Publish Year Pages File Format Full-Text
11569 747 2006 6 PDF Available
Title
Biodegradable stents with elastic memory
Abstract

This work reports, for the first time, the development of a fully biodegradable polymeric stent that can self-expand at body temperatures (∼37 °C), using the concept of elastic memory. This self-expansion is necessary in fully polymeric stents, to overcome the problem of elastic recoil following balloon expansion in a body vessel. Bi-layered biodegradable stent prototypes were produced from poly-l-lactic acid (PLLA) and poly glycolic acid (PLGA) polymers. Elastic memory was imparted to the stents by temperature conditioning. The thickness and composition of each layer in the stents are critical parameters that affect the rate of self-expansion at 37 °C, as well as the collapse strengths of the stents. The rate of self-expansion of the stents, as measured at 37 °C, exhibits a maximum with layer thickness. The Tg of the outer layer is another significant parameter that affects the overall rate of expansion.

Keywords
Self-expandable; Coronary stents; Biodegradable; Helicoid stent; Elastic recoil
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 27, Issue 8, March 2006, Pages 1573–1578
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us