fulltext.study @t Gmail

Influence of fluorapatite on the properties of thermally sprayed hydroxyapatite coatings

Paper ID Volume ID Publish Year Pages File Format Full-Text
11590 748 2004 11 PDF Available
Title
Influence of fluorapatite on the properties of thermally sprayed hydroxyapatite coatings
Abstract

Thermally sprayed hydroxyapatite has been the widely used on orthopaedic prosthesis to induce bone growth and facilitate bone attachment. However, hydroxyapatite has a greater affinity for the formation of an amorphous phase in the thermally sprayed coating that results in the release of excessive amount of mineral ions from the implant coating leading to a saturated environment in the immediate vicinity of the bone cells. Fluorapatite however is highly crystalline and offers the potential for lower mineral ion release by dissolution. Thus study investigates the influence of fluorapatite in a thermally sprayed hydroxyapatite coating. Mechanical blends of fluorapatite with hydroxyapatite were thermally sprayed, characterized with X-ray diffraction, SEM, FTIR, optical microscopy for microstructure, roughness and tested for solubility. Cathodoluminescence microscopy was used to examine the resorbed coating surface. Fluorapatite coatings crystallized more readily and produce a greater coating roughness. The roughness in fluorapatite coatings arises from less flattened droplets that show a tendency for finger formation. Addition of fluorapatite increases coating crystallinity. The use of slower resorbing fluorapatite produces less particle release which favors improved osseointegration. Less change in the surface topography during resorption can be used to an advantage to control the coating surface presented to cells and extra cellular matrix proteins.

Keywords
Hydroxyapatite; Fluorapatite; Mechanical blends; Thermal sprayed coatings; Dissolution
First Page Preview
Influence of fluorapatite on the properties of thermally sprayed hydroxyapatite coatings
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 20, September 2004, Pages 4935–4945
Authors
, ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering