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Biodegradable composite scaffolds with an interconnected spherical network for bone tissue engineering

Paper ID Volume ID Publish Year Pages File Format Full-Text
11592 748 2004 8 PDF Available
Title
Biodegradable composite scaffolds with an interconnected spherical network for bone tissue engineering
Abstract

Tissue engineering scaffolds are highly engineered structures that accommodate cells, facilitate their expression, and resorb to facilitate regeneration of tissue. A new technique for producing controlled pore shape and pore size interconnectivity offers promise for application as a tissue engineering scaffold. Salt particles were spheroidized in a flame and sintered to provide an interconnecting salt template. The salt template was filled with a carbonated fluorapatite powder and a polylactic polymer to produce a composite scaffold. It was found that a higher pore space is possible with the use of spherical and larger salt particle sizes. This technique can produce scaffolds with good interconnectivity and be suitable for producing pore size graded bodies.

Keywords
Scaffold architecture; Template; Pore connectivity; Pore shape; Salt leaching; Bone tissue scaffold
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Biodegradable composite scaffolds with an interconnected spherical network for bone tissue engineering
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 20, September 2004, Pages 4955–4962
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us