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Morphology of sol–gel derived nano-coated coralline hydroxyapatite

Paper ID Volume ID Publish Year Pages File Format Full-Text
11594 748 2004 5 PDF Available
Title
Morphology of sol–gel derived nano-coated coralline hydroxyapatite
Abstract

Current bone graft materials are mainly produced from coralline hydroxyapatite (HAp). Due to the nature of the conversion process, commercial coralline HAp has retained coral or CaCO3, and the structure possesses nanopores within the inter-pore trabeculae, resulting in high dissolution rates. Under certain conditions these features reduce durability and strength and are not utilised where high structural strength is required. To overcome these limitations, a new coral double-conversion technique has been developed.The technique involves a two-stage application route where, in the first stage, complete conversion of coral to pure HAp is achieved. In the second, a new sol–gel-derived HAp nano-coating is directly applied to cover the micro- and nano-pores within the intra-pore material, whilst maintaining the large pores. Biaxial strength was improved two-fold due to this unique double treatment. This application is expected to result in enhanced durability and longevity due to the monophasic hydroxyapatite structure and strength in the physiological environment.It is anticipated that this new material can be applied to load-bearing bone graft applications where high strength requirements are pertinent.

Keywords
Biomimetics; Bone graft; Calcium phosphate coatings; Sol–gel
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Morphology of sol–gel derived nano-coated coralline hydroxyapatite
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 20, September 2004, Pages 4971–4975
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
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Price was $35.95
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