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Improved biological performance of Ti implants due to surface modification by micro-arc oxidation

Paper ID Volume ID Publish Year Pages File Format Full-Text
11710 754 2004 9 PDF Available
Title
Improved biological performance of Ti implants due to surface modification by micro-arc oxidation
Abstract

The surface of a titanium (Ti) implant was modified by micro-arc oxidation (MAO) treatment. A porous layer was formed on the Ti surface after the oxidation treatment. The phase and morphology of the oxide layer were dependent on the voltage applied during the oxidation treatment. With increasing voltage, the roughness and thickness of the film increased and the TiO2 phase changed from anatase to rutile. During the MAO treatment, Ca and P ions were incorporated into the oxide layer. The in vitro cell responses of the specimen were also dependant on the oxidation conditions. With increasing voltage, the ALP activity increased, while the cell proliferation rate decreased. Preliminary in vivo tests of the MAO-treated specimens on rabbits showed a considerable improvement in their osseointegration capability as compared to the pure titanium implant.

Keywords
Titanium; Oxidation; Biocompatibility; In vitro; Osseointegration; In vivo
First Page Preview
Improved biological performance of Ti implants due to surface modification by micro-arc oxidation
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 14, June 2004, Pages 2867–2875
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering