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Effect of added gelatin on the properties of calcium phosphate cement

Paper ID Volume ID Publish Year Pages File Format Full-Text
11713 754 2004 7 PDF Available
Title
Effect of added gelatin on the properties of calcium phosphate cement
Abstract

This study investigates the effect of gelatin on the setting time, compressive strength, phase evolution and microstructure of calcium phosphate cement. The composite cement powder (about 18 wt% gelatin, and 82 wt% α-tricalcium phosphate) was prepared from the solid compound obtained by casting a gelatin aqueous solution containing α-tricalcium phosphate. 5 wt% of CaHPO4·2H2O were added to the powder before mixing with the liquid phase. Two cement formulations were prepared using two different liquid/powder ratios, and their properties compared with those of control samples, prepared without gelatin. The final setting time increases from 10 min to more than 45 min when the L/P ratio increases from 0.3 to 0.4 ml/g. The presence of gelatin accelerates the setting reaction, and improves the mechanical properties of the cements. The compressive strength increases with the setting reaction up to 10.7–14.0 MPa for the gelatin cements, whereas the control samples exhibit much lower values. The improved mechanical properties of the composite cements with respect to the controls can be related to their reduced total porosity and more compact microstructure.

Keywords
Calcium phosphate cement; Gelatin; Hydroxyapatite; Compressive strength; X-ray diffraction
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 14, June 2004, Pages 2893–2899
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us