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Preparation of acrylic bone cements for vertebroplasty with bismuth salicylate as radiopaque agent

Paper ID Volume ID Publish Year Pages File Format Full-Text
11860 762 2006 8 PDF Available
Title
Preparation of acrylic bone cements for vertebroplasty with bismuth salicylate as radiopaque agent
Abstract

One of the problems of percutaneous vertebroplasty attributed to the use of acrylic cements is related to the radiopacity of the formulation. The use of bismuth salicylate as the radiopaque agent is proposed in this work, taking into account the high radiopacity of organobismuth compounds used in dental applications and the possible analgesic effect of salicylic acid. Various cements formulated with this compound (some of them modified with polyethylene oxide) were examined. Setting parameters, mechanical properties, rheological behaviour, injectability, radiopacity and biocompatibility were studied for a variety of formulations, showing that the cement formulations containing bismuth salicylate have a higher radiopacity and better injection properties than commercial bone cement preparations and present good mechanical properties.

Keywords
Acrylic bone cements; Rheology; Injectability; Radiopacity
First Page Preview
Preparation of acrylic bone cements for vertebroplasty with bismuth salicylate as radiopaque agent
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 27, Issue 1, January 2006, Pages 100–107
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering