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Prediction of the frictional behavior of mammalian tissues against biomaterials

Paper ID Volume ID Publish Year Pages File Format Full-Text
1195 78 2010 8 PDF Available
Title
Prediction of the frictional behavior of mammalian tissues against biomaterials
Abstract

Frictional and adhesion properties are important characteristics to be assessed in the development of new materials for biological applications, particularly for medical devices such as catheters. In this work a new computational method that predicts frictional and adhesive forces is presented. A multi-asperities adhesion model, based on the JKR theory, coupled with a Monte Carlo method was employed, together with a three components friction model. This takes into account interfacial adhesion, asperities deformation and viscous lubricant film shearing action. We have estimated the frictional coefficients of silicone and polyurethane (common materials in catheters) against aorta and vena cava. In order to do this, we have measured the surface properties of the two blood vessels tissues, such as surface energy components, asperity height distribution and asperity radius of curvature. These data have not been previously reported. The predictions in both the dry and in lubricated (with blood) cases are in very good agreement with our published experimental data of the same materials/tissue combinations.

Keywords
Blood vessels; Adhesion; Biomaterials; Catheters; Friction
First Page Preview
Prediction of the frictional behavior of mammalian tissues against biomaterials
Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 6, Issue 10, October 2010, Pages 4052–4059
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering