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Biomaterial microarrays: rapid, microscale screening of polymer–cell interaction

Paper ID Volume ID Publish Year Pages File Format Full-Text
11964 769 2005 6 PDF Available
Title
Biomaterial microarrays: rapid, microscale screening of polymer–cell interaction
Abstract

The identification of biomaterials that induce optimal gene expression patterns and allow for appropriate levels of cellular attachment is of central importance in tissue engineering and cell therapy. Herein, we describe the creation of cell-compatible, biomaterial microarrays, that allow rapid, microscale testing of biomaterial interactions with cells. As proof of principle, we simultaneously characterized over 3456 human mesenchymal stem cell (hMSC)–biomaterial composite interactions, and describe preliminary studies on the utility of these arrays with a neural stem cell line (NSC), and primary articular chondrocytes.

Keywords
Microarray; Biomaterials; PLGA
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Biomaterial microarrays: rapid, microscale screening of polymer–cell interaction
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 26, Issue 23, August 2005, Pages 4892–4897
Authors
, , , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us