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Preparation and characteristics of a calcium magnesium silicate (bredigite) bioactive ceramic

Paper ID Volume ID Publish Year Pages File Format Full-Text
12241 786 2005 7 PDF Available
Title
Preparation and characteristics of a calcium magnesium silicate (bredigite) bioactive ceramic
Abstract

In this study, new bredigite (Ca7MgSi4O16) ceramics were prepared by sintering sol–gel-derived bredigite powder compacts at 1350 °C for 8 h. The bending strength, fracture toughness and Young's modulus were about 156 MPa, 1.57 MPa m1/2 and 43 GPa, respectively. The in vitro bioactivity of the bredigite ceramics was evaluated by investigating the apatite-formation ability in simulated body fluid (SBF) and the effect of ionic products from bredigite dissolution on the mouse fibroblasts cell line L929. In addition, the in vitro biocompatibility of the bredigite ceramics was evaluated by osteoblasts adhesion and proliferation assay. The results showed that bredigite ceramics could induce HAp formation in SBF. The products from bredigite dissolution significantly promoted cell growth at a certain concentration range. Furthermore, osteoblasts adhered and spread well on bredigite ceramics, and osteoblasts proliferation on bredigite ceramics was obvious.

Keywords
Bredigite; Bioactivity; Hydroxyapatite; Osteoblasts; Biocompatibility
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Preparation and characteristics of a calcium magnesium silicate (bredigite) bioactive ceramic
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 26, Issue 16, June 2005, Pages 2925–2931
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us