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A two year in vivo study of polyvinyl alcohol-hydrogel (PVA-H) artificial meniscus

Paper ID Volume ID Publish Year Pages File Format Full-Text
12273 786 2005 6 PDF Available
Title
A two year in vivo study of polyvinyl alcohol-hydrogel (PVA-H) artificial meniscus
Abstract

For the recognized importance of knee meniscus function, the treatment of meniscus injury has been changing from resection to repair. However, depending on the type of injury, meniscectomy sometimes cannot be avoided. In such a case, it is important to anticipate the future problem of degenerative change or osteoarthrosis in the knee joint. In consideration of the prognosis and circumstances in such patients, we have developed an artificial meniscus using polyvinyl alcohol-hydrogel (PVA-H) for salvage.We have already reported the results up to 1 year after animal operation. The present study investigated the results in postoperative 2.0 years to assess further the use of artificial meniscus.In the results, the articular cartilage state of knee joint implanted PVA-H meniscus was good even after 2 years, while Osteoarthrosis (OA) change progressed in meniscectomy knee joint. In addition, neither wear, dislocation nor breakage of PVA-H was observed.These results proved that an artificial meniscus using PVA-H can compensate for meniscal function and might be clinically applicable.

Keywords
Polyvinylalcohol; Arthritis; Knee replacement; In vivo test
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A two year in vivo study of polyvinyl alcohol-hydrogel (PVA-H) artificial meniscus
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 26, Issue 16, June 2005, Pages 3243–3248
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us