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Monitoring the degradation process of biopolymers by ultrasonic longitudinal wave pulse-echo technique

Paper ID Volume ID Publish Year Pages File Format Full-Text
12326 790 2003 6 PDF Available
Title
Monitoring the degradation process of biopolymers by ultrasonic longitudinal wave pulse-echo technique
Abstract

A non-destructive ultrasonic longitudinal wave pulse-echo technique was utilized to monitor the degradation process of three biodegradable polymers: poly(glycolic acid) (PGA), poly(l-lactic acid) (PLLA) and 50:50 poly(d,l-lactide-co-glycolide) (PDLLG). The degradation processes of PGA and PLLA, which have different molecular structure, were also studied by differential scanning calorimetry (DSC). The degradation processes of PDLLG specimens prepared by different methods were characterized by the ultrasonic wave technique and gel permeation chromatography (GPC). The resulting acoustic and thermal properties indicate that PLLA and PGA exhibit distinctly different degradation behavior, whereas the acoustic properties and molecular weight of PDLLG are sensitive with preparation methods. The present study demonstrates that ultrasonic wave technique provides a powerful tool in detecting the property changes of biodegradable polymers prepared with different manufacturing process and that the degradation behavior of biodegradable polymers can be closely monitored by ultrasonic technique.

Keywords
Ultrasonic wave; Biodegradable polymer; Poly(l-lactic acid) (PLLA); Poly(glycolic acid) (PGA); Poly(d,l-lactide-co-glycolide) (PDLLG)
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 24, Issue 22, October 2003, Pages 3871–3876
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us