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The roles of tissue engineering and vascularisation in the development of micro-vascular networks: a review

Paper ID Volume ID Publish Year Pages File Format Full-Text
12378 791 2005 19 PDF Available
Title
The roles of tissue engineering and vascularisation in the development of micro-vascular networks: a review
Abstract

The construction of tissue-engineered devices for medical applications is now possible in vitro using cell culture and bioreactors. Although methods of incorporating them back into the host are available, current constructs depend purely on diffusion which limits their potential. The absence of a vascular network capable of distributing oxygen and other nutrients within the tissue-engineered device is a major limiting factor in creating vascularised artificial tissues. Though bio-hybrid prostheses such as vascular bypass grafts and skin substitutes have already been developed and are being used clinically, the absence of a capillary bed linking the two systems remains the missing link. In this review, the different approaches currently being or that have been applied to vascularise tissues are identified and discussed.

Keywords
Micro-vascular; Tissue engineering; Capillary beds; Tissue vascularisation
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The roles of tissue engineering and vascularisation in the development of micro-vascular networks: a review
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 26, Issue 14, May 2005, Pages 1857–1875
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us