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Evaluation of mechanical properties and biological response of an alumina-forming Ni-free ferritic alloy

Paper ID Volume ID Publish Year Pages File Format Full-Text
12488 794 2005 11 PDF Available
Title
Evaluation of mechanical properties and biological response of an alumina-forming Ni-free ferritic alloy
Abstract

PM 2000 is a Ni-free oxide dispersion strengthened Fe–20Cr–5Al alloy able to develop a fine, dense and tightly adherent α-alumina scale during high-temperature oxidation. Despite the high temperature involved during thermal oxidation (1100 °C), microstructural changes in the candidate material, a hot rolled product, hardly occurs. Consequently, the good mechanical properties of the as-received material are not significantly affected. Moreover, due to the high compressive residual stresses at the alumina scale, an increase in the fatigue limit from 500 to 530 MPa is observed. Such stresses also account for the high capability of the coating/metal system to withstand more than 1% tensile deformation without cracking. The biocompatibility of the alloy was assessed in comparison to commercial alumina. Saos-2 osteoblast-like cells were either challenged with PM 2000 particles, or seeded onto PM 2000 (with and without scale) solid samples. Viability, growth, and ALP release from cells were assessed after 3 or 7 days, while mineralization was checked at 18 days. This study has demonstrated that PM 2000 with and without scale are capable of supporting in vitro growth and function of osteoblast-like cells over a period of 18 days. Results from this study suggest that the resulting alumina/alloy system combines the good mechanical properties of the alloy with the superior biocompatibility of the α-alumina, for which there is very good clinical experience.

Keywords
Steel; In vitro tests; Mechanical properties; Biocompatibility; Oxidation; Alumina; Cell culture; Surface modification
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Evaluation of mechanical properties and biological response of an alumina-forming Ni-free ferritic alloy
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 26, Issue 18, June 2005, Pages 3861–3871
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us