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Repair of segmental long bone defect in rabbit femur using bioactive titanium cylindrical mesh cage

Paper ID Volume ID Publish Year Pages File Format Full-Text
12516 795 2003 7 PDF Available
Title
Repair of segmental long bone defect in rabbit femur using bioactive titanium cylindrical mesh cage
Abstract

A segmental rabbit femur defect was repaired using an empty bioactive titanium (BAT) mesh cage. A 10 mm long titanium mesh cage was positioned in the bony defect and reinforced by intramedullary fixation. The BAT surface was prepared by chemical and thermal treatment. Pure titanium cages were used as a control. Torsional stiffness of the BAT group at 4 weeks was approximately equal to, and at 8 weeks twice, that of the intact femur. Differences between the torsional stiffness of the control and BAT groups were significant at both time intervals. Histological examinations showed that woven bone appeared around the cage by 4 weeks and transformed to lamella bone by 8 weeks. New bone bonded to the BAT surface without an intervening layer. The BAT cage enhanced the bone repairing process and achieved faster repair of long bone segmental defects.

Keywords
Titanium; Metal surface treatment; Bone repair; Osseointegration; Animal model
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Repair of segmental long bone defect in rabbit femur using bioactive titanium cylindrical mesh cage
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 24, Issue 20, September 2003, Pages 3445–3451
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us