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Adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene

Paper ID Volume ID Publish Year Pages File Format Full-Text
12602 803 2003 6 PDF Available
Title
Adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene
Abstract

We studied the adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene samples. The polymer surfaces were modified by exposure to the ultraviolet light of a Xe2*-excimer lamp at a wavelength of 172 nm in an ammonia atmosphere. Treatment times were between 10 and 20 min. The endothelial cell density was determined 1, 3 and 8 days after seeding by image analysis. Surface modification of the samples resulted in a significant increase in the number of adhering cells and in the formation of a confluent cell layer after 3–8 days. The results were comparable than those obtained on polystyrene Petri dishes, which are used as standard substrates in cell cultivation. Thus modified PTFE appears to be a promising material for the fabrication of artificial vascular prostheses coated with endothelial cells.

Keywords
Polytetrafluoroethylene; Surface treatment; Endothelial cells; Cell adhesion; Cell proliferation
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Adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 24, Issue 28, December 2003, Pages 5139–5144
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us