fulltext.study @t Gmail

Lysozyme and bovine serum albumin adsorption on uncoated silica and AlOOH-coated silica particles: the influence of positively and negatively charged oxide surface coatings

Paper ID Volume ID Publish Year Pages File Format Full-Text
12613 805 2005 7 PDF Available
Title
Lysozyme and bovine serum albumin adsorption on uncoated silica and AlOOH-coated silica particles: the influence of positively and negatively charged oxide surface coatings
Abstract

The adsorption of lysozyme and bovine serum albumin on silica and AlOOH-coated silica particles—representing negatively and positively charged oxide surfaces—was investigated. The protein-treated uncoated and completely AlOOH-coated silica particles were characterized by zeta potential analysis and UV/VIS spectroscopy. It was found that at pH 7 a protein oppositely charged to the oxide surface adsorbs in significantly higher amounts. In contrast, proteins of the same charge did not or only in very low amounts adsorbed on an oxide surface. As both oxide surfaces were measured to be very hydrophilic it can be concluded that electrostatic interactions dominate the adsorption process at the investigated experimental conditions. The pH regions where the proteins interact via attractive and repulsive coulomb interaction with the particular oxide surfaces were calculated and outlined.

Keywords
Protein adsorption; Surface charge; Silica; Alumina; Sol–gel
First Page Preview
Lysozyme and bovine serum albumin adsorption on uncoated silica and AlOOH-coated silica particles: the influence of positively and negatively charged oxide surface coatings
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 26, Issue 21, July 2005, Pages 4351–4357
Authors
, , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us