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Preparation and physicochemical properties of compression-molded keratin films

Paper ID Volume ID Publish Year Pages File Format Full-Text
12634 806 2004 8 PDF Available
Title
Preparation and physicochemical properties of compression-molded keratin films
Abstract

The S-sulfo keratin was extracted from wool and was then spray-dried to give S-sulfo keratin powder. differential scanning calorimetry analysis showed that the glass transition temperature of S-sulfo keratins became lowered with the increase of moisture content, while perfectly dried S-sulfo keratin powder did not give thermal transition in the temperature range 30–130°C. The compression molding of the S-sulfo keratin powder supplemented with one-tenth weight of water afforded a plastic-like transparent proteinous film above the glass transition temperature. The film obtained from the powder without water addition or compression molded below glass transition temperature partly remained powdery.The film compression molded at 120°C gave the maximum ultimate strength and Young’s modulus, 27.8±2.9 and 1218±80 MPa, respectively. Obtained film was insoluble and slightly swelled in water, but, in the presence of reducing agent, the film significantly swelled at pH 7.0 and even dissolved at pH 9.0, suggesting the relevance of abundant disulfide linkage. The film supported the mammalian cell adhesion and proliferation, demonstrating the biocompatibility of S-sulfo keratin films.

Keywords
Keratin; Compression molding; Biocompatibility; L929 fibroblast cell
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Preparation and physicochemical properties of compression-molded keratin films
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 12, May 2004, Pages 2265–2272
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
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Any Questions? feel free to contact us