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Development of a strontium-containing hydroxyapatite bone cement

Paper ID Volume ID Publish Year Pages File Format Full-Text
12685 810 2005 11 PDF Available
Title
Development of a strontium-containing hydroxyapatite bone cement
Abstract

A new route was developed to synthesis a new type of strontium-containing hydroxyapatite (Sr-HAP) bone cement with precursors of tetracalcium phosphate (TTCP), strontium hydrogen phosphate (DSPA), dicalcium phosphate (DCPA), phosphate acid and water. The processing parameters and fundamental properties including pH value, setting time, compressive strength of final hardened body and the cytotoxicity for serial extracts of each cements were investigated. The result shows that the final product of the cement after setting for 24 h is nonstoichiometic Sr-containing hydroxyapatite (Ca10−m−xSrx□m(HPO4)y(PO4)6−y(OH)2−2m□2m, 0

Keywords
Calcium phosphate cement; Sr-containing hydroxyapatite; Biocompatibility; Cytotoxicity
First Page Preview
Development of a strontium-containing hydroxyapatite bone cement
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 26, Issue 19, July 2005, Pages 4073–4083
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering