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Modulation of porosity in apatitic cements by the use of α-tricalcium phosphate—calcium sulphate dihydrate mixtures

Paper ID Volume ID Publish Year Pages File Format Full-Text
12718 814 2005 10 PDF Available
Title
Modulation of porosity in apatitic cements by the use of α-tricalcium phosphate—calcium sulphate dihydrate mixtures
Abstract

Calcium phosphate bone cements are injectable biomaterials that are being used in dental and orthopaedic applications through minimally invasive surgery techniques. Nowadays, apatitic bone cements based on α-tricalcium phosphate (α-TCP) are of special interest due to their self-setting behaviour when mixed with an aqueous liquid phase. In this study, a new method to improve osteointegration of α-TCP-based cements is presented. This method consists in the modification of the cement's powder phase with different amounts of calcium sulphate dihydrate (CSD). The resulting hardening properties of the new biphasic cements are a combination between the progressive hardening due to the main α-TCP reactant and the progressive dissolution of the CSD phase, which render a porous material. It was observed that the maximum compressive strength of Biocement-H© (45 MPa) decreased as the amount of CSD increased in the cement powder mixture (≈30 MPa for 25 wt% of CSD). It was also observed that after complete dissolution of the CSD phase a porous apatitic structure appears with a mechanical compressive strength suitable for cancellous bone applications (10 MPa).

Keywords
Cement; Calcium phosphate; Calcium sulphate; Physico-chemical properties
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Modulation of porosity in apatitic cements by the use of α-tricalcium phosphate—calcium sulphate dihydrate mixtures
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 26, Issue 17, June 2005, Pages 3395–3404
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us