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Calcium phosphate coating of nickel–titanium shape-memory alloys. Coating procedure and adherence of leukocytes and platelets

Paper ID Volume ID Publish Year Pages File Format Full-Text
12764 816 2003 8 PDF Available
Title
Calcium phosphate coating of nickel–titanium shape-memory alloys. Coating procedure and adherence of leukocytes and platelets
Abstract

Nickel–titanium shape-memory alloys (NiTi-SMA) were coated with calcium phosphate by dipping in oversaturated calcium phosphate solution. The layer thickness (typically 5–20 μm) can be varied by choice of the immersion time. The porous nature of the layer of microcrystals makes it mechanically stable enough to withstand both the shape-memory transition upon cooling and heating and also strong bending of the material (superelastic effect). This layer may improve the biocompatibility of NiTi-SMA, particulary for osteosynthetic devices by creating a more physiological surface and by restricting a potential nickel release. The adherence of human leukocytes (peripheral blood mononuclear cells and polymorphonuclear neutrophil granulocytes) and platelets to the calcium phosphate layer was analyzed in vitro. In comparison to non-coated NiTi-SMA, leukocytes and platelets showed a significantly increased adhesion to the coated NiTi-SMA.

Keywords
Ni–Ti shape-memory alloys; Leukocyte adherence; Metallic implants; Calcium phosphates; Coating
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Calcium phosphate coating of nickel–titanium shape-memory alloys. Coating procedure and adherence of leukocytes and platelets
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 24, Issue 21, September 2003, Pages 3689–3696
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
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Any Questions? feel free to contact us