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Albumin adsorption on alkanethiols self-assembled monolayers on gold electrodes studied by chronopotentiometry

Paper ID Volume ID Publish Year Pages File Format Full-Text
12765 816 2003 10 PDF Available
Title
Albumin adsorption on alkanethiols self-assembled monolayers on gold electrodes studied by chronopotentiometry
Abstract

Chronopotentiometry was used to study the adsorption of human serum albumin (HSA) to self-assembled monolayers with the following terminal functional groups: CH3, COOH and OH. Surfaces were characterized by X-ray photoelectron spectroscopy, water contact angle measurements and cyclic voltammetry. HSA coverage of the different SAMs was investigated by chronopotentiometry and the total amount of adsorbed protein was determined using radiolabelled albumin. Both techniques have demonstrated that HSA adsorption to the different SAM-modified electrodes increases in the following order: OH

Keywords
Albumin adsorption; Self-assembled monolayers; Electrochemistry; Chronopotentiometry; Surface modification
First Page Preview
Albumin adsorption on alkanethiols self-assembled monolayers on gold electrodes studied by chronopotentiometry
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 24, Issue 21, September 2003, Pages 3697–3706
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering