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Simple surface modification of poly(ε-caprolactone) for apatite deposition from simulated body fluid

Paper ID Volume ID Publish Year Pages File Format Full-Text
12808 818 2005 7 PDF Available
Title
Simple surface modification of poly(ε-caprolactone) for apatite deposition from simulated body fluid
Abstract

Poly(ε-caprolactone) (PCL) with a bone-like apatite layer bound to its surface could be useful as a scaffold for tissue engineering applications. In the present study, the surface of PCL was treated with aqueous NaOH to introduce carboxylate groups onto the surface. The NaOH-treated material was subsequently dipped in aqueous CaCl2 and K2HPO4·3H2O alternately three times to deposit apatite nuclei on the surface. The surface-modified material successfully formed a dense and uniform bone-like surface apatite layer after incubation for 24 h in simulated body fluid with ion concentrations approximately equal to those of human blood plasma.

Keywords
Apatite; Polycaprolactone; Simulated body fluid (SBF); Bioactivity; Scaffold; Biomimetic material
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Simple surface modification of poly(ε-caprolactone) for apatite deposition from simulated body fluid
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 26, Issue 15, May 2005, Pages 2407–2413
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us