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In situ pore formation in a polymer matrix by differential polymer degradation

Paper ID Volume ID Publish Year Pages File Format Full-Text
12893 821 2003 5 PDF Available
Title
In situ pore formation in a polymer matrix by differential polymer degradation
Abstract

A new approach for the in situ formation of porosity in a matrix based on differential polymer degradation has been studied. This approach exploits the differences in polymer properties such as molecular weight, hydrophilicity (hydrophobicity), and degradation to induce preferential degradation of one phase in a biphasic polymer system. Biphasic polymer systems polymers derived from α-hydroxy acids and poly(anhydrides), which vary in their erosion characteristics (surface vs. bulk) and hydrophobicities were studied. In addition to examining the generality of the approach, potential advantages of such systems in the context of tissue engineering and drug delivery are briefly discussed.

Keywords
Polymers; In situ porosity; Drug delivery; Tissue engineering
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 24, Issue 18, August 2003, Pages 3133–3137
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us