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Mechanical evaluation of novel spinal interbody fusion cages made of bioactive, resorbable composites

Paper ID Volume ID Publish Year Pages File Format Full-Text
12896 821 2003 10 PDF Available
Title
Mechanical evaluation of novel spinal interbody fusion cages made of bioactive, resorbable composites
Abstract

Osteoconductive and totally bioresorbable spinal/cervical interbody fusion cages were fabricated from a forged composite of raw particulate hydroxyapatite/poly l-lactide (u-HA/PLLA) with an u-HA 40 wt% fraction (F-u-HA 40). The mechanical strengths of three types of cages, designed for open-box, screw and cylinder constructs, were compared with those of existing metal and carbon-fiber/polymer cages. Compressive strengths of these composite cages surpassed those of existing metal and carbon-fiber cages. Fatigue resistance to alternate and static compressive loading persisted for longer than the minimum period (6 months) necessary for spinal devices in simulated body fluid (SBF) at 37°C. These novel interbody fusion cages await clinical application in humans.

Keywords
Bioactive/bioresorbable; Biomechanics; Spinal interbody fusion cages; Hydroxyapatite; Poly l-lactide
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Mechanical evaluation of novel spinal interbody fusion cages made of bioactive, resorbable composites
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 24, Issue 18, August 2003, Pages 3161–3170
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us