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Magnesium-sputtered titanium for the formation of bioactive coatings

Paper ID Volume ID Publish Year Pages File Format Full-Text
1292 80 2009 10 PDF Available
Title
Magnesium-sputtered titanium for the formation of bioactive coatings
Abstract

Osteoconductive coatings may improve the clinical performance of implanted metallic biomaterials. Several low-temperature coating methods have been reported where a supersaturated solution is used to deposit typically apatitic materials. However, due to the very low solubility of apatite, the concentration of calcium and phosphate ions attainable in a supersaturated solution is relatively low (∼1–2 mM), thus coating formation is slow, with several solution changes required to form a uniform and clinically relevant coating. In order to avoid this problem, we present a novel method where substrates were initially sputter coated with pure magnesium metal and then immersed in differing phosphate solutions. In this method, upon immersion the implant itself becomes the source of cations and only the anions to be incorporated into the coating are present in solution. These ions react rapidly, forming a continuous coating and avoiding problems of premature non-localized precipitation. The different coatings resulting from varying the phosphate solutions were then characterized in terms of morphology and composition by microscopy and chemical analyses. Upon immersion of the sputter-coated metals into ammonium phosphate solution, it was found that a uniform struvite (MgNH4PO4·6H2O) coating was formed. Upon subsequent immersion into a calcium phosphate solution, stable coatings were formed. The coated surfaces also enhanced both osteoblastic cellular adhesion and cell viability compared to bare titanium. The concept of sputter-coating a reactive metal to form an adherent inorganic metal coating appears promising in the field of developing rapid-forming low-temperature bioceramic coatings.

Keywords
Titanium coating; Magnesium sputtering; Struvite; Surface characterization; Osteoblast
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 5, Issue 6, July 2009, Pages 2338–2347
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us