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Effect of lipid absorption on wear and compressive properties of unirradiated and highly crosslinked UHMWPE: An in vitro experimental model

Paper ID Volume ID Publish Year Pages File Format Full-Text
12953 822 2004 6 PDF Available
Title
Effect of lipid absorption on wear and compressive properties of unirradiated and highly crosslinked UHMWPE: An in vitro experimental model
Abstract

Ultra-high molecular weight polyethylene (UHMWPE or polyethylene) components used in total joint arthroplasty absorb lipids in vivo. However, the effect, if any, of this lipid uptake on both the wear and the mechanical properties of polyethylene is not known. We contrasted the effects of lipid diffusion into the polyethylene on the wear and mechanical properties of unirradiated UHMWPE versus that into highly crosslinked UHMWPE preparation (a 95-kGy irradiated and melted UHMWPE). We doped test samples of both types of polyethylenes with either squalene alone or a 15% (w/v) solution of cholestene/squalene (CH/SQ) solution. The diffusion profiles were quantified using infrared microscopy as a function of depth away from free surfaces; we used the 1620 and 1680 cm−1 absorbances characteristic of CH and SQ, respectively. There were no statistically significant changes in the bi-directional pin-on-disk wear rates of neither type of polyethylene after lipid absorption. On the other hand, compressive modulus and compressive strength of both polyethylenes decreased after doping with either lipid.

Keywords
Total joint arthroplasty; UHMWPE; Crosslinking; Wear; Compressive properties; Lipid absorption
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Effect of lipid absorption on wear and compressive properties of unirradiated and highly crosslinked UHMWPE: An in vitro experimental model
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 18, August 2004, Pages 4479–4484
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us