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Shear-load carrying capacity of cancellous bone after implantation of self-reinforced polyglycolic acid and poly-l-lactic acid pins: experimental study on rats

Paper ID Volume ID Publish Year Pages File Format Full-Text
12973 823 2001 5 PDF Available
Title
Shear-load carrying capacity of cancellous bone after implantation of self-reinforced polyglycolic acid and poly-l-lactic acid pins: experimental study on rats
Abstract

Both distal femora of 40 rats were implanted with a self-reinforced polyglycolic acid (SR-PGA) pin in the right femur and with a self-reinforced poly-l-lactic acid (SR-PLLA) pin in the left femur. The intact femora of 20 rats served as controls. The follow-up times were 1, 3, 6, 12, 24, 36, 48, and 52 weeks. After killing all operated and control femora were examined macroscopically and radiographically. The shear-load carrying capacities of all the femurs were investigated, and the SR-PGA and SR-PLLA fixed specimens were compared with each other and with the control specimens. The shear-load carrying capacities reached their highest values at 36 weeks in the SR-PGA and SR-PLLA fixed and control specimens. Thereafter they gradually decreased. At 52 weeks both the SR-PGA fixed specimens and the control specimens had statistically significantly (p<0.001) higher values than the SR-PLLA fixed specimens, when the influence of the pins had ceased. Otherwise, the shear-load capacities showed higher values in the SR-PLLA fixed specimens, as the pins carried the load. During the whole follow-up period the mean shear-load carrying capacity of the SR-PGA fixed specimens was 171.2 N and that of the SR-PLLA fixed specimens 180.9 N, the corresponding value of the control specimens was 148.2 N.

Keywords
Cancellous bone; Shear-load; Polyglycolide; Poly-l-lactide; Pin
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Shear-load carrying capacity of cancellous bone after implantation of self-reinforced polyglycolic acid and poly-l-lactic acid pins: experimental study on rats
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 22, Issue 18, September 2001, Pages 2557–2561
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us