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Inkjet printing for high-throughput cell patterning

Paper ID Volume ID Publish Year Pages File Format Full-Text
13050 828 2004 9 PDF Available
Inkjet printing for high-throughput cell patterning

The adaptation of inkjet printing technology to the complex fields of tissue engineering and biomaterial development presents the potential to increase progress in these emerging technologies through the implementation of this high-throughput capability via automated processes to enable precise control and repeatability. In this paper, a method of applying high-throughput inkjet printing to control cellular attachment and proliferation by precise, automated deposition of collagen is presented. The results indicate that commercial inkjet printing technology can be used to create viable cellular patterns with a resolution of 350 μm through the deposition of biologically active proteins. This method demonstrates a combination of off-the-shelf inkjet printing and biomaterials and has potential to be adapted to tissue engineering and colony patterning applications. Adapting this method into the three-dimensional construction of cellular structures for eventual high-throughput tissue engineering using a bottom-up approach is possible.

Tissue engineering; Micro patterning; Collagen; Hydrogel; Inkjet printing; Surface modification
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Inkjet printing for high-throughput cell patterning
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 17, August 2004, Pages 3707–3715
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Physical Sciences and Engineering Chemical Engineering Bioengineering