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Preparation of chitosan/ethylcellulose complex microcapsule and its application in controlled release of Vitamin D2

Paper ID Volume ID Publish Year Pages File Format Full-Text
13079 829 2002 5 PDF Available
Title
Preparation of chitosan/ethylcellulose complex microcapsule and its application in controlled release of Vitamin D2
Abstract

A system which consists of chitosan (CS) microcores entrapped within enteric polymer is investigated. Vitamin D2 (VD2) used as a model drug, was efficiently entrapped in CS microcores using spray drying and was microencapsulated by coating of ethylcellulose. The morphology and release properties of microcapsules were tested. The factors which influenced the preparation, including molecular weight of CS, concentration of CS solution, concentration of acetic acid and loading of VD2, were discussed. The results of release in vitro showed that the microcapsules could realize sustained release in intestine juice.

Keywords
Microcapsule; Chitosan; Vitamin D2
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Preparation of chitosan/ethylcellulose complex microcapsule and its application in controlled release of Vitamin D2
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 23, Issue 23, December 2002, Pages 4469–4473
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us