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Easy assessment of the biocompatibility of Ni–Ti alloys by in vitro cell culture experiments on a functionally graded Ni–NiTi–Ti material

Paper ID Volume ID Publish Year Pages File Format Full-Text
13088 829 2002 7 PDF Available
Title
Easy assessment of the biocompatibility of Ni–Ti alloys by in vitro cell culture experiments on a functionally graded Ni–NiTi–Ti material
Abstract

The biocompatibility of nickel–titanium alloys was investigated by single-culture experiments on functionally graded samples with a stepwise change in composition from pure nickel to pure titanium, including an Ni–Ti shape memory alloy for a 50:50 mixture. This approach permitted a considerable decrease of experimental resources by simultaneously studying a full variation of composition. The results indicate a good biocompatibility for a nickel content up to about 50%. The cells used in the biocompatibility studies comprised osteoblast-like osteosarcoma cells (SAOS-2, MG-63), primary human osteoblasts (HOB), and murine fibroblasts (3T3).

Keywords
Ni–Ti shape memory alloys; Biocompatibility; Metallic implants; Nickel alloys; Titanium alloys
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Easy assessment of the biocompatibility of Ni–Ti alloys by in vitro cell culture experiments on a functionally graded Ni–NiTi–Ti material
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 23, Issue 23, December 2002, Pages 4549–4555
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us