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Hydrolytic degradation study of biodegradable polyesteramide copolymers based on ε-caprolactone and 11-aminoundecanoic acid

Paper ID Volume ID Publish Year Pages File Format Full-Text
13117 832 1981 7 PDF Available
Title
Hydrolytic degradation study of biodegradable polyesteramide copolymers based on ε-caprolactone and 11-aminoundecanoic acid
Abstract

In this paper, a new kind of aliphatic biodegradable polyesteramide copolymers P(CL/AU)x/y based on ε-caprolactone and 11-aminoundecanoic acid were synthesized by the melt polycondensation method. Hydrolytic degradation behavior of P(CL/AU) copolymers were studied by using FTIR, 1H-NMR and DSC. Chemical compositions, macromolecular weight, thickness of the test sample, and pH of the degradation medium have great effect on degradation rate. The degradation rate decreased with increase in aminoundecanoic acid content, macromolecular weight, and thickness of the test samples, but increased with incubation temperature and pH of the degradation medium. The degradation mechanism was studied according to the mathematical model developed by professor Göpferich.

Keywords
Polyesteramide; ε-caprolactone; Hydrolytic degradation; Degradation mechanism
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Hydrolytic degradation study of biodegradable polyesteramide copolymers based on ε-caprolactone and 11-aminoundecanoic acid
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 11, May 2004, Pages 1975–1981
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us