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Electrochemically assisted co-precipitation of protein with calcium phosphate coatings on titanium alloy

Paper ID Volume ID Publish Year Pages File Format Full-Text
13221 843 2004 9 PDF Available
Title
Electrochemically assisted co-precipitation of protein with calcium phosphate coatings on titanium alloy
Abstract

A bovine serum albumin protein-containing calcium phosphate coating (BSA/brushite) was prepared by electrochemically assisted co-precipitation onto a hydroxyapatite (HA) coated Ti-6Al-4 V surface. Electrochemically assisted co-precipitation of BSA/brushite coatings onto HA resulted in a 70-fold increase in BSA inclusion compared to simple adsorption, and was subsequently released by a slower mechanism (15% loss over 70 h). Thus, this electrochemically assisted co-precipitation technique provides an efficient method of protein incorporation at physiological temperature, with a potential for sustained release of therapeutic agents as may be required for metallic implant fixation.

Keywords
Hydroxyapatite; Cacium phosphate; Titanium alloy; Protein; Electrochemical incorporation
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Electrochemically assisted co-precipitation of protein with calcium phosphate coatings on titanium alloy
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 23, October 2004, Pages 5395–5403
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
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