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Fluoridated hydroxyapatite coatings on titanium obtained by electrochemical deposition

Paper ID Volume ID Publish Year Pages File Format Full-Text
1337 81 2009 10 PDF Available
Title
Fluoridated hydroxyapatite coatings on titanium obtained by electrochemical deposition
Abstract

Hydroxyapatite (HA) and fluoridated hydroxyapatite (FHA) coatings were deposited on titanium substrates using an electrochemical technique. Different concentrations of F− ions were incorporated into the apatite structure by adding NaF into the electrolyte. Typical apatite structures were obtained for all the coatings after electrodeposition and subsequent post-treatment, including alkaline immersion and vacuum calcination. The coatings were uniform and dense, with a thickness of ∼5 μm. When the F-concentration was higher than 0.012 M in the electrolyte, a saturation of F in the coating occurred and the F/Ca ratio in the coatings became almost constant (F/Ca ratio = 0.125). The FHA coatings showed higher bonding strength and lower dissolution rate than HA coating, particularly for those with a fluoridation level of 0.5–0.625. Compared with pure Ti, FHA and HA coatings exhibited higher biological affinity like cell proliferation and alkaline phosphatase activity. Regarding clinical application, it is suggested that a moderate content of F, such as Ca5(PO4)3(OH)0.375−0.5F0.5−0.625, be most suitable as a compromise among cell attachment, cell proliferation, apatite deposition and dissolution resistance.

Keywords
Fluoridated hydroxyapatite; Electrochemical deposition; Dissolution rate; Cellular responses
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 5, Issue 5, June 2009, Pages 1798–1807
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us