fulltext.study @t Gmail

Stability of plasma-treated silicone rubber and its influence on the interfacial aspects of blood compatibility

Paper ID Volume ID Publish Year Pages File Format Full-Text
13393 853 2004 15 PDF Available
Title
Stability of plasma-treated silicone rubber and its influence on the interfacial aspects of blood compatibility
Abstract

Medical-grade polydimethylsiloxane elastomer was subjected to low-powered plasma treatment in the presence of four different gases: O2, Ar, N2 and NH3. Changes to the surface chemistry immediately after processing and the stability of the treatments following ageing in phosphate buffered saline or air for up to 1 month were investigated using X-ray photoelectron spectroscopy and dynamic contact angle analysis. Changes in surface morphology were assessed using optical microscopy and atomic force microscopy. All treatments resulted in an increase in wettability, attributed to major changes in chemistry combined with modest etching. Furthermore, the primary site of attack of the plasma species appeared to be dependent upon the feed gas implemented. The two main chemical changes observed after ageing were due to reactions with the storage media and relaxation processes resulting in further changes in wettability. The influence of the surface modifications on the blood compatibility of the materials was investigated by assessing contact phase activation using a partial thromboplastin time assay. It was demonstrated that the O2 and Ar plasma treatments reduced the performance of the silicone but the N2 and NH3 treatments had a significantly beneficial effect on the activation of the coagulation cascade.

Keywords
Silicone; Surface modification; Gas plasma; Blood compatibility; Coagulation
First Page Preview
Stability of plasma-treated silicone rubber and its influence on the interfacial aspects of blood compatibility
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 25, Issue 19, August 2004, Pages 4659–4673
Authors
, , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us