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Initial tissue response to a titanium implant coated with apatite at room temperature using a blast coating method

Paper ID Volume ID Publish Year Pages File Format Full-Text
13417 855 2002 6 PDF Available
Title
Initial tissue response to a titanium implant coated with apatite at room temperature using a blast coating method
Abstract

We previously reported a blast coating method (BC method) as a new coating method of titanium (Ti) with apatite (AP) at room temperature. The BC method gives much stronger AP coating on the Ti surface compared with those obtained by other room temperature coating methods. However, no in vivo study has been made, so far, to evaluate the stability or the tissue response to the implant. As an initial step to evaluate the feasibility of the BC method, we evaluated the tissue response and stability of AP coated Ti implant prepared with the BC method (AP–BC implant) using rats as experimental animals. The AP coating adhered tightly to the Ti surface even after the implant procedure and throughout the experimental period up to six weeks post operation. AP–BC implant caused no inflammatory response, showed strong bone response and much better osteoconductivity compared with the pure Ti implant. The new bone formed on the surface of AP–BC implants was thinner compared with that formed on the surface of Ti implant. Therefore, the AP–BC implant has a good potential as an osteoconductive implant material.

Keywords
Blast coating; Apatite; Titanium
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Initial tissue response to a titanium implant coated with apatite at room temperature using a blast coating method
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 23, Issue 9, May 2002, Pages 1931–1936
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us