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Bone modeling controlled by a nickel–titanium shape memory alloy intramedullary nail

Paper ID Volume ID Publish Year Pages File Format Full-Text
13446 856 2002 9 PDF Available
Title
Bone modeling controlled by a nickel–titanium shape memory alloy intramedullary nail
Abstract

Nitinol (NiTi) shape memory metal alloy makes it possible to prepare functional implants that apply a continuous bending force to the bone. The purpose of this study was to find out if bone modeling can be controlled with a functional intramedullary NiTi nail. Pre-shaped intramedullary NiTi nails (length 26 mm, thickness 1.0–1.4 mm) with a curvature radius of 25–37 mm were implanted in the cooled martensite form in the medullary cavity of the right femur in eight rats, where they restored their austenite form, causing a bending force. After 12 weeks, the operated femurs were compared with their non-operated contralateral counterpairs. Anteroposterior radiographs demonstrated significant bowing, as indicated by the angle between the distal articular surface and the long axis of the femur (p=0.003). Significant retardation of longitudinal growth and thickening of operated femurs were also seen. Quantitative densitometry showed a significant increase in the average cross-sectional cortical area (p=0.001) and cortical thickness (p=0.002), which were most obvious in the mid-diaphyseal area. Cortical bone mineral density increased in the proximal part of the bone and decreased in the distal part. Polarized light microscopy of the histological samples revealed that the new bone induced by the functional intramedullary nail was mainly woven bone. In conclusion, this study showed that bone modeling can be controlled with a functional intramedullary nail made of nickel–titanium shape memory alloy.

Keywords
Nitinol; Bone modeling; Intramedullary nailing; pQCT; Bone mineral density
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Bone modeling controlled by a nickel–titanium shape memory alloy intramedullary nail
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 23, Issue 12, June 2002, Pages 2535–2543
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us