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Hepatocyte performance on different crystallographic faces of rutile

Paper ID Volume ID Publish Year Pages File Format Full-Text
13487 859 2003 6 PDF Available
Title
Hepatocyte performance on different crystallographic faces of rutile
Abstract

The influence of crystallographic orientation of polished rutile single crystal surfaces of the (1 0 0), (1 1 0) and (1 1 1) orientation on hepatocyte performance was tested in cell culture over 3 days. Cell adhesion was observed on the titanium dioxide surfaces and their performance was measured by means of cell number attached (protein mass), cell viability (neutral red assays) and metabolic activity (thiazolyl tetrazolium bromide assay).Titanium dioxide displays no cytotoxic effects on hepatocytes, and shows a performance in the range of standard collagen-coated tissue culture polystyrene dish. The number of hepatocytes adhered on the different rutile surfaces were not significantly different to those on dense rutile polycrystalline ceramic.These findings suggest that hepatocytes do not recognize the specific differences of differently orientated rutile crystal surfaces.

Keywords
Hepatocyte adhesion; Rutile crystal; MTT; NR
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 24, Issue 15, July 2003, Pages 2605–2610
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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Full-text PDF Download
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Any Questions? feel free to contact us