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Biocompatibility studies of new multiblock poly(ester–ester)s composed of poly(butylene terephthalate) and dimerized fatty acid

Paper ID Volume ID Publish Year Pages File Format Full-Text
13699 892 2002 6 PDF Available
Title
Biocompatibility studies of new multiblock poly(ester–ester)s composed of poly(butylene terephthalate) and dimerized fatty acid
Abstract

This study was undertaken to evaluate the biocompatibility of new multiblock poly(ester–ester)s proposed as an alternative to Hunter silastic prosthesis used in a two-stage tendon reconstruction. Methanol-extracted polymeric material retained its weight, demonstrating the absence of leachable particles (e.g. low-molecular weight oligomers). Implantation tests indicated that the observed tissue changes were similar to those obtained with silicone, no evidence of contact necrosis being observed. The unchanged morphology of rat liver hepatocytes and the lack of parenchymal necrosis also indicated that exposure to the investigated polymers did not cause any cytotoxic reactions.

Keywords
Multiblock copolyester; Artificial tendon; Dimerized fatty acid; Aromatic polyester
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Biocompatibility studies of new multiblock poly(ester–ester)s composed of poly(butylene terephthalate) and dimerized fatty acid
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 23, Issue 14, July 2002, Pages 2973–2978
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us