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Role of acid attack in the in vitro bioactivity of a glass-ceramic of the 3CaO·P2O5-CaO·SiO2-CaO·MgO·2SiO2 system

Paper ID Volume ID Publish Year Pages File Format Full-Text
13820 913 2013 7 PDF Available
Title
Role of acid attack in the in vitro bioactivity of a glass-ceramic of the 3CaO·P2O5-CaO·SiO2-CaO·MgO·2SiO2 system
Abstract

A non-bioactive glass-ceramic (GC13) that contains hydroxyapatite (Ca5(PO4)3OH), diopside (CaMg(SiO3)2) and althausite (Mg2PO4OH) as crystalline phases has been obtained by thermal treatment of a parent bioactive glass (G13) of nominal composition (wt%) 40.0 CaO–34.5 SiO2–16.5 P2O5–8.5 MgO–0.5 CaF2. To induce bioactivity, GC13 was chemically treated with 1 m HCl for different periods of time. After chemical etching the in vitro studies showed formation of an apatite-like surface layer. In this article the influence of etching time both on the surface composition of the glass-ceramic and on the growth rate of the apatite layer is studied. It is concluded that the presence of hydroxyapatite in the glass-ceramic, associated to microstructural fluctuations, can favour apatite deposition in vitro.

Keywords
Bioactive glass-ceramics; Bioceramics; In vitro studies; Bioactivity induction; Surface morphology
First Page Preview
Role of acid attack in the in vitro bioactivity of a glass-ceramic of the 3CaO·P2O5-CaO·SiO2-CaO·MgO·2SiO2 system
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 22, Issue 14, 2001, Pages 2013–2019
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering