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Bone bonding behavior of the hydroxyapatite containing glass–titanium composite prepared by the Cullet method

Paper ID Volume ID Publish Year Pages File Format Full-Text
13832 915 2001 8 PDF Available
Title
Bone bonding behavior of the hydroxyapatite containing glass–titanium composite prepared by the Cullet method
Abstract

Bioactive composites composed of hydroxyapatite containing glass (HA–G) as a coating and titanium (Ti) or titanium alloy implants as a substrate were prepared by the Cullet method. This method results in the HA–G coating layer on the substrate with a compositional gradient in HA concentration. The results of in vitro and in vivo experiments investigating the characteristics of the composite materials are reported and discussed in this article. In vitro evaluations confirmed that the Cullet method was suitable for the preparation of the functionally gradient composite implants with higher reliable quality. In vivo experiments permitted evaluation of bonding strength of these composite implants to living bone tissue. Mechanical pull-out tests indicated that the implants bonded to living bone at least as firmly as those by the conventional method, and that the adhesion between the HA–G coating layer and metal substrate was well integrated and strongly maintained in vivo. SEM observations with EDX and a histological study of the interface between the HA–G–Ti composite implants and bone tissue revealed not only that the implants bonded to bone directly without any intervening tissue but that bone ingrowth into the HA–G layer occurred. The HA–G–Ti composite implants demonstrate both biocompatible and osteoconductive characteristics, and may be expected to obtain good and lasting results when applied clinically.

Keywords
Implant; Hydroxyapatite-containing glass; Biomaterial; Bone bonding; Artificial joint
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Bone bonding behavior of the hydroxyapatite containing glass–titanium composite prepared by the Cullet method
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 22, Issue 16, 15 August 2001, Pages 2207–2214
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us