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Static and dynamic in vitro study of a sol–gel glass bioactivity

Paper ID Volume ID Publish Year Pages File Format Full-Text
13842 915 2001 6 PDF Available
Title
Static and dynamic in vitro study of a sol–gel glass bioactivity
Abstract

A comparative study of in vitro bioactivity of a sol–gel glass with composition 55% SiO2–41% CaO–4%P2O5 has been carried out by soaking it in a simulated body fluid (SBF) with and without exchange of this solution. When SBF is kept constant (static assay) the solution composition changes, increasing the Ca2+ concentration and pH as a function of soaking time while these parameters remain nearly constant and very close to human conditions in dynamic conditions. Glass surface is studied by FTIR, XRD and SEM in order to compare the behaviour in the two procedures, revealing that in both cases an apatite-like layer is formed on the glass surface, although there are differences in rate and morphology in this formation. In addition, a study of porosity was carried out by Hg intrusion pointing out the pore distribution and changes in porosity with time for both procedures. A similar behaviour in mesopore region was detected, while macropores remain nearly constant in static conditions, decreasing from 0.48 to 0.12 μm in just 3 h of soaking in dynamic assay.

Keywords
Bioactive sol–gel glasses; CaO–P2O5–SiO2 system; Static and dynamic in vitro studies; Porosity
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 22, Issue 16, 15 August 2001, Pages 2301–2306
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us