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Effect of citric acid on the nucleation of hydroxyapatite in a simulated body fluid

Paper ID Volume ID Publish Year Pages File Format Full-Text
13946 977 1999 6 PDF Available
Title
Effect of citric acid on the nucleation of hydroxyapatite in a simulated body fluid
Abstract

The role of citric acid in a simulated body fluid (SBF) was examined with the main focus on its induction ability of hydroxyapatite (HAp) nucleation on a bioinert collagen membrane. Collagen membranes were soaked in the SBF with citric acid concentrations in the range of 0–4 mm; then, carbonate-containing HAp crystals grew within a limited range, i.e., 0.3–2 mm. The results were explained in terms of chemical interaction among calcium ion, citric acid and collagen membrane, especially strong chelation ability of citric acid with the calcium ion.

Keywords
Hydroxyapatite; Citric acid; Collagen membrane; Simulated body fluid; Nucleation
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Effect of citric acid on the nucleation of hydroxyapatite in a simulated body fluid
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 20, Issue 22, November 1999, Pages 2155–2160
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us