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Hybrid biomaterials based on the interaction of polyurethane oligomers with porcine pericardium

Paper ID Volume ID Publish Year Pages File Format Full-Text
13994 996 1996 10 PDF Available
Title
Hybrid biomaterials based on the interaction of polyurethane oligomers with porcine pericardium
Abstract

Hybrid biomaterials have been produced by the interaction of polyurethane oligomers with both fresh and glutaraldehyde-fixed porcine pericardium. The hybrid biomaterials so formed were translucent with occasional white streaks and/or spots, had increased stiffness (to touch) but remained pliable. No shrinkage temperature was detected for fresh porcine pericardium hybrid up to 100 °C compared to porcine pericardium (~67 °C) and glutaraldehyde-fixed porcine pericardium (~87 °C). Amino acid analysis of the fresh porcine pericardium hybrid showed a reduction in lysine content after active isocyanate-terminated polyurethane oligomers exposure, indicating cross-linking between the polymer and tissue. Histological examination of the hybrid material shows a thin grey coating on both surfaces of the tissue, implying at least surface cross-linking of the tissue with polyurethane. The results suggest that fresh porcine pericardium can be reacted with active isocyanate-terminated polyurethane oligomers to produce hybrid biomaterials with covalent bonding.

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Hybrid biomaterials based on the interaction of polyurethane oligomers with porcine pericardium
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 17, Issue 22, November 1996, Pages 2163-2172
Authors
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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Online Support
Any Questions? feel free to contact us